Journal of Aging Science

Department of Medicine, University of Paris, Paris, France

Biography

Patrice Codogno is working in INEm of paris, currently working with 4 projects and had published 383 articles till date in international journals. One of the projects major objective is to identify and explain correlations between the regulation of autophagy and chemoresistance

Publications

• Review Article   
  Healthy Aging Biology, Powerful Insight from the Long-Lived Naked Mole-Rat
  Author(s): Frédéric Saldmann, Mélanie Viltard*, Christine Leroy, Patrice Codogno and Gérard Friedlander
  
  The naked mole-rat, Heterocephalus glaber, is the longest-lived rodent known with a lifespan in captivity >30 years, 10 times longer than mice, a comparable size rodent. In addition to a particularly long life, it exhibits exceptional resistance to many age-related diseases: cancer, cardiovascular, neurodegenerative, and metabolic diseases. It resists many forms of stress: hypoxia, oxidative stress, and strikingly maintains adequate body composition, fertility, bone quality, and mineral density throughout their long life. The naked mole-rat is a non-traditional animal model that defies the law governing the processes of aging and mortality and provides a powerful tool for the discovery of endogenous molecular anti-aging pathways. Over the past decades, much possible resistance and anti-aging mechanisms have been discovered. These include exclusive physiologica.. View more»
  

  DOI: 10.35248/2329-8847.21.9.258

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