Dr, Fondation Pour La Recherche En Physiologie, Brussels, Belgium
Melanie Viltard is working in the Foundation For Research In Physiology, Brussels, Belgium. Till date Melanie viltard had published 38 publications which influenced readers to acquire more information related to the study.
Review Article
Healthy Aging Biology, Powerful Insight from the Long-Lived Naked Mole-Rat
Author(s): Frédéric Saldmann, Mélanie Viltard*, Christine Leroy, Patrice Codogno and Gérard Friedlander
The naked mole-rat, Heterocephalus glaber, is the longest-lived rodent known with a lifespan in captivity >30 years,
10 times longer than mice, a comparable size rodent. In addition to a particularly long life, it exhibits exceptional
resistance to many age-related diseases: cancer, cardiovascular, neurodegenerative, and metabolic diseases. It resists
many forms of stress: hypoxia, oxidative stress, and strikingly maintains adequate body composition, fertility, bone
quality, and mineral density throughout their long life. The naked mole-rat is a non-traditional animal model that
defies the law governing the processes of aging and mortality and provides a powerful tool for the discovery of
endogenous molecular anti-aging pathways. Over the past decades, much possible resistance and anti-aging
mechanisms have been discovered. These include exclusive physiologica.. View more»