Zeteo Biomedical LLC, PO Box 342216, Austin, TX 78734, USA
Sullivan T.R. is presently running as a Professor withinside the Department of Medicine; Rift valley fever (RVF); RVF virus; RVF arMP-12ΔNSm21/384 vaccine; RVF antibody; Intranasal vaccination. Sullivan T.R. has authored many studies articles/books associated with Medicine. Sullivan T.R. is serving as an article member and reviewer of numerous worldwide reputed journals. Sullivan T.R. has efficiently finished his Administrative responsibilities. Sullivan T.R. studies hobbies consist of Medicine; Rift valley fever (RVF); RVF virus; RVF arMP-12ΔNSm21/384 vaccine; RVF antibody; Intranasal vaccination.
Research Article
Assessment of the Immunogenicity of a Novel Live Recombinant Rift Valley Fever arMP-
12ΔNSm21/384 Vaccine Candidate Following Intranasal Vaccination of Goats, Sheep
and Calves in Tanzania
Author(s): Nyundo S., Adamson E.K., Rowland J., Palermo P.M., Salekwa L., Matiko M.K., Bettinger G.E., Wambura P., Morrill J.C., Sullivan T.R. and Watts D.M.*
Background: Rift Valley fever virus (RVFV) is an arbovirus that causes morbidity and mortality in livestock and
humans throughout Africa and in the Arabian Peninsula. Vaccines are effective for the prevention of Rift Valley
fever (RVF) disease, but new and improved vaccines are needed to improve the safety of available vaccines. Also, non-invasive
needle free vaccine delivery routes should be evaluated as an alternative for invasive routes of vaccination.
Objective: The aim of this proof of concept study was to evaluate the safety and immunogenicity of a novel live
attenuated recombinant RVFV arMP-12ΔNSm21/384 vaccine candidate following intranasal vaccination of goats,
calves, and sheep in Tanzania.
Methods: Healthy, 6-9 months old breeds of African sheep (Ovis aeris), goats (Capra aegagrus) and z.. View more»