Department of Biology, Laboratory of Population Genetics and Computational Evolutionary Biology- LaBECom, UNIVISA, Vitória de Santo Antão, Pernambuco, Brazil
Robson da Silva Ramos is currently working as a Professor in the Department of Biology at the Laboratory of Population Genetics and Computational Evolutionary Biology. His research interests include Medicine. Robson da Silva Ramos is serving as an editorial member and reviewer of several international reputed journals. Robson da Silva Ramos has successfully completed his Administrative responsibilities. Robson da Silva Ramos has authored of many research articles/books related to Medicine.
Research Article
Molecular Diversity Analysis of the Spike (S) Glycoprotein Gene from Hong Kong-China
Author(s): Eduarda Doralice Alves Braz da Silva, Dallynne Bárbara Ramos Venâncio, Rosane Maria de Albuquerque, Robson da Silva Ramos and Pierre Teodósio Felix*
In this work, 37 haplotypes of spike glycoprotein of SARS-CoV-2 from Hong Kong, China, were used. All sequences were publicly available on the platform of the National Center for Biotechnology Information (NCBI) and were analyzed for their Molecular Variance (AMOVA), haplotypic diversity, mismatch, demographic and spatial expansion, molecular diversity and time of evolutionary divergence. The results suggested that there was a low diversity among haplotypes, with very low numbers of transitions, transversions, indels-type mutations and with total absence of population expansion perceived in the neutrality tests. The estimators used in this study supported the uniformity among all the results found and confirm the evolutionary conservation of the gene, as well as its protein product, a fact that stimulates the use of therapies based on neutralizing antibodies, such as vaccines based on.. View more»