Journal of Vaccines & Vaccination

Department of Biology, Laboratory of Population Genetics and Computational Evolutionary Biology- LaBECom, UNIVISA, Vitória de Santo Antão, Pernambuco, Brazil

Biography

Eduarda doralice alves braz da silva is currently working as a Professor in the Department of Biology. His research interests includes Biologiccal studies. He is serving as an editorial member and reviewer of several international reputed journals. He has successfully completed his Administrative responsibilities. He has authored of many research articles/books related to Biological Sciences.

 

Publications

• Research Article   
  Molecular Diversity Analysis of the Spike (S) Glycoprotein Gene from Hong Kong-China
  Author(s): Eduarda Doralice Alves Braz da Silva, Dallynne Bárbara Ramos Venâncio, Rosane Maria de Albuquerque, Robson da Silva Ramos and Pierre Teodósio Felix*
  
  In this work, 37 haplotypes of spike glycoprotein of SARS-CoV-2 from Hong Kong, China, were used. All sequences were publicly available on the platform of the National Center for Biotechnology Information (NCBI) and were analyzed for their Molecular Variance (AMOVA), haplotypic diversity, mismatch, demographic and spatial expansion, molecular diversity and time of evolutionary divergence. The results suggested that there was a low diversity among haplotypes, with very low numbers of transitions, transversions, indels-type mutations and with total absence of population expansion perceived in the neutrality tests. The estimators used in this study supported the uniformity among all the results found and confirm the evolutionary conservation of the gene, as well as its protein product, a fact that stimulates the use of therapies based on neutralizing antibodies, such as vaccines based on.. View more»
  

  DOI: 10.35248/2157-7560.21.12.442

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