Journal of Vaccines & Vaccination

Department of Biology, Laboratory of Population Genetics and Computational Evolutionary Biology- LaBECom, UNIVISA, Vitória de Santo Antão, Brazil

Biography

I have a Bachelor's Degree in Biological Sciences from the Federal Rural University of Pernambuco in 2000, a Master's Degree in Genetics from the Federal University of Pernambuco in 2002 and a PhD in Genetics from the Federal University of Pernambuco in 2013. I am currently Professor, Researcher and Research Coordinator at UNIVERSITY CENTER OF VITÓRIA DE SANTO ANTÃO (UNIVISA), I lead the GROUP OF RESEARCH IN POPULATION AND EVOLUTION GENETICS (GPOP) and I am chief researcher at the LABORATORY OF POPULATION GENETICS and COMPUTATIONAL EVOLUTIONARY BIOLOGY (LaBECom). 

Publications

• Research Article   
  Molecular Diversity Analysis of the Spike (S) Glycoprotein Gene from Hong Kong-China
  Author(s): Eduarda Doralice Alves Braz da Silva, Dallynne Bárbara Ramos Venâncio, Rosane Maria de Albuquerque, Robson da Silva Ramos and Pierre Teodósio Felix*
  
  In this work, 37 haplotypes of spike glycoprotein of SARS-CoV-2 from Hong Kong, China, were used. All sequences were publicly available on the platform of the National Center for Biotechnology Information (NCBI) and were analyzed for their Molecular Variance (AMOVA), haplotypic diversity, mismatch, demographic and spatial expansion, molecular diversity and time of evolutionary divergence. The results suggested that there was a low diversity among haplotypes, with very low numbers of transitions, transversions, indels-type mutations and with total absence of population expansion perceived in the neutrality tests. The estimators used in this study supported the uniformity among all the results found and confirm the evolutionary conservation of the gene, as well as its protein product, a fact that stimulates the use of therapies based on neutralizing antibodies, such as vaccines based on.. View more»
  

  DOI: 10.35248/2157-7560.21.12.442

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