PhD, FRSM, Gulf Coast Biologics, Scientific and Research Department, 4331 Veronica S. Schoemaker Blvd., Suite 4, Fort Myers, FL 33916, USA
Peter A. Everts, belonging to Gulf Coast Biologics, Scientific and Research Department, Fort Myers FL, USA. Interested in the field of Cell culture and manufacture, Stem cell therapy.
Research Article
A Comparative Quantification in Cellularity of Bone Marrow Aspirated with two New Harvesting Devices, and The Non-equivalent Difference Between A Centrifugated Bone Marrow Concentrate And A Bone Marrow Aspirate As Biological Injectates, Using A Bi-Lateral Patient Model
Author(s): Peter A. Everts*, John Ferrell, Christine Brown Mahoney, Glenn Flanagan II, Moises Irizarry-de Roman, Rowan Paul, Natalie Stephens and Kenneth Mautner
The first aim of this study was to examine the cellularity and quality of autologous bone marrow aspirates harvested with two novel FDA-cleared devices, namely the Aspire™ bone marrow aspiration system (AS-BMAS) and the Marrow Cellution bone marrow aspiration device (MC-BMAD). Compared to traditional bone marrow harvesting needle systems, both these devices have a closed distal tip, avoiding preferential marrow collection (peripheral blood aspiration) from deeper cavity regions, whereas the side holes facilitate more horizontal marrow extraction. In all patients, a similar harvesting technique was used. The second aim was to demonstrate the effectiveness of mechanical centrifugation of a large volume of extracted bone marrow to produce a bone marrow concentrate (BMC). Finally, we directly compared bone marrow constituents aspirated with MC-BMAD with a BMC, generated by centrifug.. View more»