Journal of Stem Cell Research & Therapy

Biosciences Research Associates, Cambridge MA, USA

Biography

Natalie Stephens, belonging to Biosciences Research Associates, Cambridge MA, USA. Interested in the field of Cell culture and manufacture , Stem cell therapy.

Publications

• Research Article   
  A Comparative Quantification in Cellularity of Bone Marrow Aspirated with two New Harvesting Devices, and The Non-equivalent Difference Between A Centrifugated Bone Marrow Concentrate And A Bone Marrow Aspirate As Biological Injectates, Using A Bi-Lateral Patient Model
  Author(s): Peter A. Everts*, John Ferrell, Christine Brown Mahoney, Glenn Flanagan II, Moises Irizarry-de Roman, Rowan Paul, Natalie Stephens and Kenneth Mautner
  
  The first aim of this study was to examine the cellularity and quality of autologous bone marrow aspirates harvested with two novel FDA-cleared devices, namely the Aspire™ bone marrow aspiration system (AS-BMAS) and the Marrow Cellution bone marrow aspiration device (MC-BMAD). Compared to traditional bone marrow harvesting needle systems, both these devices have a closed distal tip, avoiding preferential marrow collection (peripheral blood aspiration) from deeper cavity regions, whereas the side holes facilitate more horizontal marrow extraction. In all patients, a similar harvesting technique was used. The second aim was to demonstrate the effectiveness of mechanical centrifugation of a large volume of extracted bone marrow to produce a bone marrow concentrate (BMC). Finally, we directly compared bone marrow constituents aspirated with MC-BMAD with a BMC, generated by centrifug.. View more»
  

  Abstract PDF