Emory University, Department of Physical Medicine & Rehabilitation & Department of Orthopedics, Atlanta,GA, USA
Kenneth Mautner, belonging to Emory University, Department of Physical Medicine & Rehabilitation & Department of Orthopedics, Atlanta,GA, USA. Interested in the field of Stem cell therapy, Tissue engineering.
Research Article
A Comparative Quantification in Cellularity of Bone Marrow Aspirated with two New Harvesting Devices, and The Non-equivalent Difference Between A Centrifugated Bone Marrow Concentrate And A Bone Marrow Aspirate As Biological Injectates, Using A Bi-Lateral Patient Model
Author(s): Peter A. Everts*, John Ferrell, Christine Brown Mahoney, Glenn Flanagan II, Moises Irizarry-de Roman, Rowan Paul, Natalie Stephens and Kenneth Mautner
The first aim of this study was to examine the cellularity and quality of autologous bone marrow aspirates harvested with two novel FDA-cleared devices, namely the Aspire™ bone marrow aspiration system (AS-BMAS) and the Marrow Cellution bone marrow aspiration device (MC-BMAD). Compared to traditional bone marrow harvesting needle systems, both these devices have a closed distal tip, avoiding preferential marrow collection (peripheral blood aspiration) from deeper cavity regions, whereas the side holes facilitate more horizontal marrow extraction. In all patients, a similar harvesting technique was used. The second aim was to demonstrate the effectiveness of mechanical centrifugation of a large volume of extracted bone marrow to produce a bone marrow concentrate (BMC). Finally, we directly compared bone marrow constituents aspirated with MC-BMAD with a BMC, generated by centrifug.. View more»