Department of Basic Science, Graduate School of Arts and Sciences, The University of Tokyo, Komaba, Meguro, Tokyo,, Japan
Taro Toyota belong to the Department of Basic Science and he graduated from school of arts and sciences from the university of tokyo in the Komaba, Meguro, Tokyo, Japan Taro Toyota International experience includes various programs, contributions and participation in different countries for diverse fields of study.
Mini Review Article
Physicochemical Cause and Effect Observed in DNA Length-Dependent
Division of Protocell as the Primitive Flow of Information
Author(s): Muneyuki Matsuo, Kensuke Kurihara, Taro Toyota, Kentaro Suzuki and Tadashi Sugawara*
In the prebiotic era, physicochemical cause and effect served as the primitive flow of information for protocells.
Our recent study claimed that the manners and frequencies of self-reproduction of giant vesicle (GV) -based model
protocells were regulated by the incorporated DNA-length, and not the base-pair sequence due to the presence of a
supramolecular catalyst (lipo-deoxyribozyme) composed of DNA and lipophilic catalysts. The DNA-length dependent
dynamics of the self-reproducing GVs containing different length of DNA were examined by three independent
experiments; Population analysis by flow cytometric measurements, counting of???increased numbers of protocells
and direct morphological observation of a single GV by confocal microscopy. These results may shed light on the
information system in the prebiotic stage, when the central dogma was not established. Notably, recent r.. View more»