Department of Chemistry, Faculty of Science, Hiroshima University, Kagamiyama, Higashi-hiroshima, Hiroshima 739-8526Japan, Japan
Muneyuki Matsuo works in the Department of Chemistry as a Faculty of Science in the Hiroshima University, Kagamiyama, Higashi-hiroshima, Hiroshima 739-8526, Japan Muneyuki Matsuo International experience includes various programs, contributions and participation in different countries for diverse fields of study.
Mini Review Article
Physicochemical Cause and Effect Observed in DNA Length-Dependent
Division of Protocell as the Primitive Flow of Information
Author(s): Muneyuki Matsuo, Kensuke Kurihara, Taro Toyota, Kentaro Suzuki and Tadashi Sugawara*
In the prebiotic era, physicochemical cause and effect served as the primitive flow of information for protocells.
Our recent study claimed that the manners and frequencies of self-reproduction of giant vesicle (GV) -based model
protocells were regulated by the incorporated DNA-length, and not the base-pair sequence due to the presence of a
supramolecular catalyst (lipo-deoxyribozyme) composed of DNA and lipophilic catalysts. The DNA-length dependent
dynamics of the self-reproducing GVs containing different length of DNA were examined by three independent
experiments; Population analysis by flow cytometric measurements, counting of???increased numbers of protocells
and direct morphological observation of a single GV by confocal microscopy. These results may shed light on the
information system in the prebiotic stage, when the central dogma was not established. Notably, recent r.. View more»