Advances in Pharmacoepidemiology and Drug Safety

Department of Pharmacy, University of Dhaka, Bangladesh

Biography

Sitesh C Bachar currently works at the Department of Pharmacy, Faculty of Pharmacy, University of Dhaka. His research interests are on Medicinal Chemistry, Pharmacological evaluation of Bangladeshi Medicinal Plants, BE study of generic formulations, Rational Use of Drugs in clinical settings, Qualitative Evaluation and Development of Herbal and Traditional Medicines, Drug Product Designing and Development etc.

Publications

• Research   
  Tigecycline in CR-Kp Associated VAP with High Dose vs. Conventional Dose: Adverse Events are the Key Superiority-determiner
  Author(s): Md Jahidul Hasan*, Raihan Rabbani, Shihan Mahmud Redwanul Huq and Sitesh Chandra Bachar
  
  Background: Multi-drug Resistant (MDR) pathogen Carbapenem-Resistance Klebsiella pneumonia (CR-Kp) associated Ventilator-Associated Pneumonia (VAP) is a serious infectious disease and tigecycline with high or conventional dose, is one of the last resort potential antibiotics for its treatment. Objective: The major objective of this study was to evaluate the key role of adverse events in preferring the better dosing option of tigecycline. Methods: Total 45 middle-aged MDR-CR-Kp associated VAP patients and treated with high (200 mg/day) and conventional dose (100 mg/day) of tigecycline (intravenous) distributed into two groups. Group-wise microbiological eradication rate, secondary infection rate, 30 days mortality rate and dose-related adverse events were analyzed and compared, accordingly. .. View more»
  

  DOI: 10.35248/2167-1052.20.9.227

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