National Clinical Research Center of Kidney Disease, Jinling hospital, Nanjing Medical University, Najing 210002, Jiangsu, China
Shijun Li is an Associated chief physician in Department of Geriatric Cardiology, Chinese PLA General Hospital, PR China.He worked in Department of Cardiology, Dalian Zhongshan Geriatric hospital, Dalian, China. He did his Doctorate in Health Science Center of Peking University and masters in Dalian Medical University.
Research Article
Association of Low Serum Complement 3 with Worse Glomerular Filtration Rate in Patients with IgA Nephropathy Secondary to Psoriasis
Author(s): Da-feng He, Rong Wang, Chun-lei Lu, Shi-jun Li, Chang-hua Liu, Cai-hong Zeng and Zheng Tang*
Objective: Complement system is pivotal in the pathogenesis of psoriasis and IgA Nephropathy (IgAN). Few studies have examined the features of patients with IgAN secondary to Psoriasis (IgAN-Pso). The association of serum complement and renal function is unknown. This study was made to investigate the relationship between serum C3 and glomerular filtration rate in patients with IgAN-Pso.
Methods: In this retrospective cross-sectional study, eighty-five patients with IgAN without evidence of a secondary cause other than psoriasis were enrolled. Patients were divided into two groups: the serum ≥ 0.9 g/L group (n=56) and the serum <0.9 g/L group (n=29). We used CKD-EPI equation to estimate Glomerular Filtration Rate (eGFR) and Empower Stats software to assess the relationship study.
Results: Patients with low se.. View more»