Journal of Stem Cell Research & Therapy

Stem Cells 21 Co. Ltd, Bangkok, 10330, Thailand

Biography

Sergey V. Dmitriev was born in 1961 in Tomsk, Russia. Dmitriev graduated from Tomsk State University with M.S. degree in 1984. Dmitriev completed the Ph.D. degree in structural mechanics at Tver State University, Russia, in 1988. Dmitriev gained the second Ph.D. degree in computer modeling of incommensurate phases in dielectrics from the University of Electro-Communications, Tokyo, Japan, in 1999. 

Publications

• Research Article   
  Robust, Efficient and Pure Induced Mesenchymal Stem Cells Generation from mRNA Induced Pluripotent Stem Cells in Suspension
  Author(s): Rajneesh Verma*, Pornpun Saengmuang, Tanabodee Payuha, Julie D Mendoza, Rotsarin Narang, Naphapatsorn Bondee, Sergei Dmitrievs and Paul Michael Collier
  
  Mesenchymal Stem Cells (MSCs) are involved in many promising clinical trials tackling vastly complicated diseases. Many factors are determining the safety in these clinical trials such as the purity of tissue-derived MSCs cell population used in therapies. Also, the efficacy of the injected MSCs must be tested in-vitro, before application, through proliferation capacity and reproducibility over continuous passages. In addition to, the importance of choosing the right source of MSCs derivation for successful cellular therapy and transplantation. This study demonstrates robust generation of iMSCs from induced Pluripotent Stem Cells (iPSC) of healthy human donor (with full genetic test done prior) using non-integrative (mRNA) method. This conversion method comprises (i) differentiating a population of iPSCs in suspension without iMatrix, (ii) passaging the cells differentiated i.. View more»
  

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