Journal of Stem Cell Research & Therapy

Stem Cells 21 Co. Ltd, Bangkok, 10330, Thailand

Biography

Paul Collier is Deputy Director of the MBA Program. His background includes roles as CFO and General Manager of a listed manufacturing company and Head of Training for a police force. He joined Monash in 2006 after having spent 7 years at Aston Business School in the UK. At Monash Paul has been a Professor of Accounting.

Publications

• Research Article   
  Robust, Efficient and Pure Induced Mesenchymal Stem Cells Generation from mRNA Induced Pluripotent Stem Cells in Suspension
  Author(s): Rajneesh Verma*, Pornpun Saengmuang, Tanabodee Payuha, Julie D Mendoza, Rotsarin Narang, Naphapatsorn Bondee, Sergei Dmitrievs and Paul Michael Collier
  
  Mesenchymal Stem Cells (MSCs) are involved in many promising clinical trials tackling vastly complicated diseases. Many factors are determining the safety in these clinical trials such as the purity of tissue-derived MSCs cell population used in therapies. Also, the efficacy of the injected MSCs must be tested in-vitro, before application, through proliferation capacity and reproducibility over continuous passages. In addition to, the importance of choosing the right source of MSCs derivation for successful cellular therapy and transplantation. This study demonstrates robust generation of iMSCs from induced Pluripotent Stem Cells (iPSC) of healthy human donor (with full genetic test done prior) using non-integrative (mRNA) method. This conversion method comprises (i) differentiating a population of iPSCs in suspension without iMatrix, (ii) passaging the cells differentiated i.. View more»
  

  Abstract PDF