Journal of Nanomedicine & Nanotechnology

Abionic SA, Route de la Corniche 5, Epalinges, Switzerland

Biography

Patrick van den Bogaard is affiliated to Abionic SA, Route de la Corniche 5. He is a recipient of many awards and grants for his valuable contributions and discoveries in major area of subject research. His international experience includes various programs, contributions and participation in different countries for diverse fields of study.  His research interests reflect in his wide range of publications in various national and international journals.
 

Publications

• Research   
  Nanofluidics Drives Point-of-care Technology for on the Spot Protein Marker Analysis with Rapid Actionable Results
  Author(s): Laur�©anne Putallaz, Patrick van den Bogaard, Priscille Laub and Fabien Rebeaud*
  
  Protein sensing in a nanofluidic environment dramatically shortens immunoassay time-to-result through the combined action of efficient mass transfer and short diffusion distances. Here, we report on a fully automated point-of-care in vitro diagnostic platform based on disposable capsule containing nanofluidic sensors in which fluorescent immunoassays are performed. Performances of the system were established with three model assays for ferritin, immunoglobulin E (IgE) and pancreatic stone protein (PSP). The described system has the typical high capture efficiency of nano-confined spaces combined with forced-flow, which induce a constant maximal concentration gradient on the sensor. Remarkably, analytes are detected in zeptomole quantities from a drop of blood. Dose-response curves show that high precision and accuracy are achieved in the clinically relevant assay ranges. Moreover, acc.. View more»
  

  DOI: 10.35248/2157-7439.19.10.536

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