Boehringer Ingelheim, Animal Health Research and Development, Ames, IA, USA
Joseph R. Hermann is currently working as a Animal Health Researcher. His research interests includes Virus, Virus diseases, vaccination, aerosols. He is serving as an editorial member and reviewer of several international reputed journals. He has successfully completed his Administrative responsibilities. Joseph R. Hermann has authored of many research articles/books related to Animal health.
Research Article
Efficacy of Porcine Circovirus Type 2a and 2d Based Vaccines Following PCV2 Challenge
Author(s): Rachel Friedrich, Abby R. Patterson, Wesley Johnson, Brian Fergen, Bernd Grosse Liesner and Joseph R. Hermann*
This study evaluated the efficacy of PCV2a and PCV2d vaccines against a PCV2 challenge. Three-week-old, cesarean-derived, colostrum-deprived pigs were blocked by litter and randomized to treatment group. Pigs received a single 2 mL intramuscular dose of either placebo (PLAC, n=50), PCV2a vaccine (PCV2aV, n=25), or PCV2d vaccine (PCV2dV, n=25) on D0 and were challenged with a PCV2d isolate on D28. Prior to challenge, a naturally occurring PCV2a infection was identified. Both vaccines similarly prevented lymphoid tissue lesions, mortality and clinical signs of PCVAD while PLAC pigs were severely affected. Viremia was significantly reduced 7, 14, 21, and 28 days post-c.. View more»