Journal of Vaccines & Vaccination

Boehringer Ingelheim Vetmedica, Inc. Binger Str. 173, Ingelheim, Germany

Biography

Bernd Grosse Liesner is currently working as a Professor in the Department of Medicine. His research interests includes Medicine. He is serving as an editorial member and reviewer of several international reputed journals. He has successfully completed his Administrative responsibilities. He has authored of many research articles/books related to Medicine.

Publications

• Research Article   
  Efficacy of Porcine Circovirus Type 2a and 2d Based Vaccines Following PCV2 Challenge
  Author(s): Rachel Friedrich, Abby R. Patterson, Wesley Johnson, Brian Fergen, Bernd Grosse Liesner and Joseph R. Hermann*
  
  This study evaluated the efficacy of PCV2a and PCV2d vaccines against a PCV2 challenge. Three-week-old, cesarean-derived, colostrum-deprived pigs were blocked by litter and randomized to treatment group. Pigs received a single 2 mL intramuscular dose of either placebo (PLAC, n=50), PCV2a vaccine (PCV2aV, n=25), or PCV2d vaccine (PCV2dV, n=25) on D0 and were challenged with a PCV2d isolate on D28. Prior to challenge, a naturally occurring PCV2a infection was identified. Both vaccines similarly prevented lymphoid tissue lesions, mortality and clinical signs of PCVAD while PLAC pigs were severely affected. Viremia was significantly reduced 7, 14, 21, and 28 days post-c.. View more»
  

  Abstract PDF