Stony Brook Southampton Hospital, Department of Internal Medicine, Southampton, NY, USA
Research Article
Chest CT versus RT-PCR for Diagnostic Accuracy of COVID-19 Detection: A Meta-Analysis
Author(s): Daisy Young, Liana Tatarian, Ghulam Mujtaba, Priscilla Chow, Samer Ibrahim, Gunjan Joshi, HaarisNaji, Phillip Berges, Krishna Akella, Howard Sklarek, Kashif Hussain and Akella Chendrasekhar*
Background: The rapid outbreak of COVID-19 has necessitated expedient methods of detection to prevent further spread and mortality from the virus. Currently, RT-PCR is considered the gold standard. However, its diagnostic priority compared to Chest CT remains unknown. Objective: We sought to perform a meta-analysis using retrospective studies comparing Chest CT and RT-PCR in COVID-19 detection among hospitalized patients. Methods: We performed a comprehensive literature search using Pubmed and Google Scholar for studies comparing Chest CT and RT-PCR between January 1 and April 3, 2020. Outcomes included COVID-19 detection using RT-PCR alone, Chest CT alone, true positives when combining the two, and true negatives when combining the two. Results were reported as an odds ratio (OR) with 95% CI. Results: A total of 6 re.. View more»