Richmond University Medical Center, Staten Island, NY, USA
Dr. Akella Chendrasekhar is a general surgeon in Staten Island, New York and is affiliated with Richmond University Medical Center. He received his medical degree from University of Miami Miller School of Medicine and has been in practice for more than 20 years.
Research Article
Chest CT versus RT-PCR for Diagnostic Accuracy of COVID-19 Detection: A Meta-Analysis
Author(s): Daisy Young, Liana Tatarian, Ghulam Mujtaba, Priscilla Chow, Samer Ibrahim, Gunjan Joshi, HaarisNaji, Phillip Berges, Krishna Akella, Howard Sklarek, Kashif Hussain and Akella Chendrasekhar*
Background: The rapid outbreak of COVID-19 has necessitated expedient methods of detection to prevent further spread and mortality from the virus. Currently, RT-PCR is considered the gold standard. However, its diagnostic priority compared to Chest CT remains unknown. Objective: We sought to perform a meta-analysis using retrospective studies comparing Chest CT and RT-PCR in COVID-19 detection among hospitalized patients. Methods: We performed a comprehensive literature search using Pubmed and Google Scholar for studies comparing Chest CT and RT-PCR between January 1 and April 3, 2020. Outcomes included COVID-19 detection using RT-PCR alone, Chest CT alone, true positives when combining the two, and true negatives when combining the two. Results were reported as an odds ratio (OR) with 95% CI. Results: A total of 6 re.. View more»