Journal of Tropical Diseases & Public Health

Biochemistry Department, University of Lausanne, 1066 Epalinges, Switzerland

Biography

Giampietro Corradin graduated in chemistry at the University of Padua and received his PhD degree in chemistry from the University of California, Santa Barbara, after completion of a thesis on the structure and function of cytochrome c. After a post-doctoral position in biochemistry at Dartmouth Medical School, Hanover, New Hampshire, he continued his training in molecular immunology at the National Jewish Hospital, Denver, Colorado. He joined the Institute of Biochemistry in 1979 where he was an Associate Professor.

Publications

• Original Research Article   
  Seroreactivity of Populations Living in Endemic Area of Burkina Faso to Plasmodium falciparum Alpha-Helical Coiled Coil Proteins Motifs by Protein Microarray
  Author(s): Oumarou Ouédraogo*, Luisa Nunziangeli, Edith C. Bougouma, Youssouf Kaboré, Amidou Diarra, Blami Koté, Alfred B. Tiono, Giampietro Corradin, Valentina Mangano, David Modiano, Yves Traoré, Sodiomon B. Sirima, Roberta Spaccapelo and Issa Nébié
  
  The naturally acquired immunity is one of the models of immunity that is exploited for malaria antigens discovery. We have used multiplex protein microarrays of 92 P. falciparum alpha-helical coiled coil protein motifs to screen plasma samples obtained from 1113 children and adults belonging to three sympatric ethnic groups from malaria endemic area of Burkina Faso. We have investigated the influence of some factors such as age, ethnicity, hemoglobin genotype and sex on the antigens reactivity and the IgG antibody level. We also investigated specifically, the influence of the factors mentioned above on the 36 antigens with the highest antibody prevalence and intensity. As expected, the findings of the study confirmed the positive correlation between age, antigens reactivity and IgG antibody level. Except for three antigens (MSP2_3D7, MR260, and As182.20), the IgG level was hi.. View more»
  

  DOI: 10.35248/2329-891X.19.7.320

  Abstract HTML PDF