Journal of Vaccines & Vaccination

Department of Medicine, Tufts University School of Medicine, Boston, MA, USA

Biography

Florence Comite is currently working as a Professor in the Department of Medicine. Her research interests includes Immunology, Virology, Vccination. She is serving as an editorial member and reviewer of several international reputed journals. She has successfully completed her Administrative responsibilities. Florence Comite has authored of many research articles/books related to Immunology, Vccination, Virology.

 

Publications

• Research Article   
  Clinical Utility of Corona Virus Disease-19 Immunoglobulin G, M, Spike Protein, and Neutralizing Antibodies in Health, Disease and Post-Vaccination
  Author(s): Ernst J. Schaefer, Florence Comite, Latha Dulipsingh, Maxine Lang, Jessica Jimison, Martin M. Grajower, Nathan E. Lebowitz, Andrew S. Geller, Margaret R. Diffenderfer, Lihong He, Gary Breton, Michael L. Dansinger, Ben Saida, Chong Yuan and R. Travis Wilkes
  
  Objective: About 80% of corona virus disease-19 (COVID-19) deaths due to severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection occur in subject’s ≥ 65 years of age, even though subjects in this age group only account for about 10% of COVID-19 cases. Our objectives were to assess age effects and the clinical utility of COVID-19 antibody levels in health, disease, and post-vaccination. Methods: We measured serum SARS-CoV-2 immunoglobulin M (IgM), IgG and neutralizing antibodies using immunoassay kits obtained from Diazyme (Poway, CA) and spike (S) protein antibodies using immunoassay kits obtained from Roche Diagnostics (Indianapolis, IN). Results: In 79,005 subjects, IgG and IgM levels were positive (≥1.0 arbitrary units [AU]/mL) in 5.29% and 3.25% of subjects, respectively.. View more»
  

  DOI: 10.35248/2157-7560.21.s12.003

  Abstract HTML PDF