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Fabíola Marques de Carvalho
Department of Bioinformatics, National Laboratory of Scientific Computation, Petrópolis, Brazil
Biography
Fabíola Marques de Carvalho is currently working as a Professor in the Department of Bioinformatics. His research interests includes Bioinformatics. He is serving as an editorial member and reviewer of several international reputed journals. Fabíola Marques de Carvalho has successfully completed his Administrative responsibilities. Fabíola Carvalho has authored of many research articles/books related to Bioinformatics, Infections.
Publications
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Research Article
Insights of How Lung Microbiome can Contribute to COVID-19 Severity in Intensive Care Unit Patients
Author(s): Fabíola Marques de Carvalho, Leandro Nascimento Lemos, Luciane Prioli Ciapina, Rennan Garcias Moreira, Alexandra Gerber, Ana Paula C. Guimarães, Tatiani Fereguetti, Virgínia Antunes de Andrade Zambelli, Renata Avila, Tailah Bernardo de Almeida, Jheimson da Silva Lima, Shana Priscila C. Barroso, Mauro Martins Teixeira, Renan Pedra Souza, Cynthia Chester Cardoso, Renato Santana Aguiar and Ana Tereza R. de Vasconcelos*
Objectives: Secondary bacterial and fungal infections are associated with respiratory viral infections and invasive mechanical ventilation. Microbiome influence on COVID-19 severity in patients admitted to intensive care units (ICU) remains poorly understood. This work described the lung microbiota of Brazilian COVID-19 patients and explored how microbial pathogens can contribute to Coronavirus disease 2019 clinical outcome. Methods: Total DNA of bronchoalveolar lavage fluids from 21 Brazilian COVID-19 patients was extracted. All patients were positive RT-PCR and admitted to intensive care units in two Brazilian centers. For metagenomic analyses, sequenced reads were submitted to bioinformatic tools for taxonomic and functional inferences. Results: We identified respiratory, nosocomial, and opportunistic pat.. View more»