Department of Internal Medicine, Beilinson Hospital, Rabin Medical Centre, Israel
Ela Giladiis working as professor in Department of Internal Medicine “C”, Beilinson Hospital, Rabin Medical Center, Petah-Tikva, Israel . Research experience includes various programs, contributions and participation in different countries for diverse fields of Medical sciences, Health Services, Health Safety.
Research Article
Apixaban in Elderly Patients with Atrial Fibrillation and Renal Dysfunction: Findings from A National Registry
Author(s): Ela Giladi*, Chen Gurevitz, Robert Klempfner, Ilan Goldenberg and Avishay Elis
Background: We aimed to evaluate the clinical characteristics and outcomes of patients 75 years and older with
atrial fibrillation (AF) and renal dysfunction who are treated with apixaban.
Methods: A sub analysis of a multicenter prospective cohort registry, where consecutive eligible apixaban or warfarin
treated patients with non-valvular AF and renal impairment (eGFR MDRD<60 ml/min/BSA) were registered. All
patients were prospectively followed-up for clinical events and dosing adjustments over a mean period of 1 year. The
current sub analysis focused on the subjects aged ≥75 years. The primary outcomes were 1 year: mortality, stroke or
systemic embolism, major bleeding and myocardial infarction as well as their composite occurrence.
Results: In the subjects 75 years or older with renal impai.. View more»