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Zhang Shang
Department of General Surgery, China
Publications
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Review Article
Preoperative Cancer Nano medicine: Neoadjuvant Chemotherapy, Radiation, Immunotherapy, And Phototherapy Made Possible by Nanotechnology
Author(s): Zhang Shang*
Malignant solid tumours are still mostly treated with surgical resection. However, in the past 10 years, there has been an increase in interest in the use of neo-adjuvant therapies, such as chemotherapy, radiation, phototherapy, and immunotherapy, either alone or in combination, as a preoperative intervention regimen [1]. The survival rates of long-term neoadjuvant treatment and adjuvant therapy have not been significantly different in early randomised, controlled studies in several tumour situations. However, due to the clear down staging of primary tumours to define the surgical margin, the ability to tailor systemic therapy response as a clinical tool to optimise subsequent therapeutic regimens, and the reduction in the need for surgery with its potential for increased morbidity, neoadjuvant treatments are being used more frequently in clinical p.. View more»