Department of Otorhinolaryngology, Children’s Hospital of Nanjing Medical University, 72 Guangzhou Road, Nanjing, Jiangsu Province 210008, China
Brief Report
Glucocorticoid Receptor Expression in Torus Tubarius Hypertrophy Tissue Causing Secretory Otitis Media in Children
Author(s): Zhi-Pan Teng, Qi Li* and Xiao-Fei Shen*
Background: Torus Tubarius Hypertrophy (TTH) after adenoidectomy causing nasal obstruction, recurred snoring, sleep apnea, or mouth breathing has been reported more and more recently, partial resection of TTH conducted by a low-temperature plasma technique is a safe and effective therapy and some benefit from intranasal steroid therapy. However, the expression of Glucocorticoid Receptor (GCR) in TTH tissue is currently unknown and no paper reported secretory otitis media caused by TTH.
Objectives: To assess the expression patterns of the human GCR in TTH tissue in children and report secretory otitis media caused by TTH.
Methods: 5 children from Jan to Jun 2024 were included in this study. All children underwent partial resection of TTH and TTH tissues were collected for immunofluorescence.
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