Department of Clinical Microbiology, National Institute of Respiratory Diseases (INER), Mexico City, Mexico
Research Article
A Comparison between GeneXpert Testing and the Berlin-Charite Diagnostic Protocol for the Detection of SARS-CoV-2 in a Cohort of Mexican Patients
Author(s): Eduardo Becerril-Vargas*, Gabriel Cojuc-Konigsberg, Gastón Becherano-Razon, Ángel Sánchez-Tinajero, Yessica Saraí Velazco-García, José Arturo Martínez-Orozco, Andrea Iraís Delgado-Cueva, Danna Patricia Ruiz-Santillán, Antonio- Juárez Etzael, Rodríguez-Sánchez Víctor Manu, Valencia-Trujillo Daniel, García Colín María del Carmen, Mujica- Sánchez Mario, Mireles-Dávalos Christian Daniel, Montiel Molina Yamil Baruch, Daniel de la Rosa Martinez and Diana Vilar-Compte
Since the beginning of the SARS-CoV-2 pandemic healthcare professionals have found it necessary to generate diagnostic methods for the disease that are easy to use, reliable, and accessible.
The Berlin-Charité protocol has been one of the most recommended methods for detecting SARS-CoV-2 from the onset of the pandemic. However, new diagnostic techniques such as GeneXpert have been developed and proven to be efficient, fast, and easy to use to detect infected patients.
The purpose of this study, conducted at the National Institute for Respiratory Diseases in Mexico, was to compare the diagnostic performance of the Berlin-Charité protocol and GeneXpert for the detection of SARS-CoV-2, evaluating a cohort of 135 Mexican patients. For statistical analysis, sensitivity, specificity, positive predictive value, negative predictive value, and likelihood ratio.. View more»