Department of Pharmacy Practice, Regis University, Denver, USA
Research Article
Drug-Induced Xerostomia: The Physical, Mental, and Economic Impact
Author(s): Leticia A. Shea*, Vahram Ghushchyan and Madalyn Kuhlenberg
Background: Many medications utilized in the United States (US) cause xerostomia (dry mouth); however, the costs
and Quality Of Life (QOL) reduction associated with this side effect remains to be determined.
Objective: To estimate the annual dental expenditures and quality of life burden attributable to chronic use of
medications that cause xerostomia in the US adult population.
Methods: This was a cross-sectional retrospective analysis evaluating prescribed medications in 2019 as reported
by the Medical Expenditure Panel Survey. Medications were organized in 2 groups: medications with and without
documentation of xerostomia. The treatment group included the US non-institutionalized adult population with
chronic use of xerostomia causing medications. The control group included the rest of the US non-inst.. View more»