Advances in Pharmacoepidemiology and Drug Safety

Department of Pharmacovigilance, Research and pharmaceutical development Laboratory, University hospital establishment of Oran, Algeria

Biography

Dr. Hechmi TOUMI graduated from the University Blaise Pascal, Researcher assistant at Wisconsin University and awarded professor at the University of Wales, UK. He is currently a research professor of Muscular Skeletal Pathology, the Dean of the Faculty of Science and Technology at the Orleans University France, Vice Director Laboratory EA 4708 - I3MTO and Vice President of the Institute of Research, Treatment & Prevention of Osteoporosis. Hechmi Toumi founded Demasq, Cardiff UK Limited in February 2008 and also serves as its Chief Scientific Officer.

Publications

• Research Article   
  DILI Causality Assessment Methods Comparison: CIOMS Scale Versus Non-Specific Methods
  Author(s): Amina Berradia*, Fznmekaouche, Fetati H and Toumi H
  
  The Pharmacovigilance Department of the University Hospital establishment Oran (UHEO) collects, evaluates and monitors adverse drug reactions (ADRs) with corrective or preventive measures taken within UHEO. Faced with the divergence of causality assessment results in drug induced liver injury (DILI) cases during our practice, we conducted a study to compare the results of non-specific and specific causality assessment method (CAM). A comparative study spanning June 2011 to August 2017 was conducted on the archived statements of ADRs at the pharmacovigilance department or on new declarations from various UHEO departments. A special sheet has been designed to collect the information needed to assess causality. After collecting informations, the causality was assessed by combining non-specific CAMs (Naranjo et al. /Bégaud et al.) with a DILI-specific CAM (t.. View more»
  

  DOI: 10.35248/2167-1052.20.9.232

  Abstract HTML PDF