Journal of Liver

Department of Pharmacy Practice, Amrita School of Pharmacy, Amrita Vishwa Vidyapeetham, Kochi, 682041, Kerala, India

Publications

• Review Article   
  A Review on Frailty in Patient with Liver Cirrhosis and Its Management
  Author(s): Thasneem S*, Yedu Krishnan SS, Roshni PR and Shine Sadasivan
  
  Frailty is an unstable phenomenon affecting multiple physiological systems, resulting in decreased reserve and vulnerable outcomes. With ageing the prevalence of frailty seems to be increasing general population as well as with cirrhosis patients. Though research are undergoing on prognostic markers, gut microbes or pharmacology in hepatology, it should be extended to a proper definition for frailty its diagnostic tool and management. Frailty score should be considered along with MELD score as a routine assessment in patients waiting for liver transplantation. Malnutrition is a common complication of cirrhosis patients which may leads to frailty, even though frailty is seen in well-nourished patients. When normal dietary supplements become ineffective the need for nutritional supplements like Branched chain amino acids (BCAA) become necessary. Combining BCAAs along with exercise thera.. View more»
  

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