Toyo Hospital, Tokushima, Japan
Research Article
A Low Gluten Diet Suppresses Disease Activity of Rheumatoid Arthritis
Author(s): Kenji Tani*, Hinako Takagishi, Yoshihiro Okura, Shingo Kawaminami, Keisuke Kawahito, Keisuke Inaba, Kaori Inaba, Akiko Miyatake, Keisuke Kondo, Yoshinori Nakanishi, Ryo Tabata, Teruki Shimizu and Harutaka Yamaguchi
Background: This study aimed to evaluate the efficacy of a low gluten diet in the disease activity of Rheumatoid
Arthritis (RA).
Methods: Among 109 patients with RA enrolled in this study, 98 patients who completed 16 weeks on a low gluten
diet regimen were included in the study. At baseline, we gave the patients the information about gluten-free and
gluten-contained foods, and asked them to refrain from the daily gluten consumption during the experimental
period.
Results: The low gluten diet significantly improved DAS28-CRP and CDAI scores after 16 weeks. The percentages
of patients achieving DAS28-CRP and CDAI-defined remission or LDA were significantly increased after 16 weeks.
There was a significant increase in the percentage of the responders in EULAR treatment response after 16 weeks.
Rheuma.. View more»