Institute of Molecular Biology and Biotechnology (IMBB), The University of Lahore, KM Defence Road, Lahore, Pakistan Postal code: 58810, Pakistan
Review Article
Formulation, Optimization and Dissolution of Piper Nigrum Nanosuspension.
Author(s): Ume Habiba and Sumaira Sharif
The aim of present study was to enhance the dissolution rate of Piper nigrum, plant extract by formulating its nanosuspension.
Piperine which is the main bioactive constituent of Piper nigrum is responsible for its bioactivities. Nanoprecipitation
approach was used for the formulation of nanosuspension. The present research was divided into different phases. The first
phase of this study was consisting of formulation and optimization of formulative parameters for the preparation of a stable
nanosuspension of Piper nigrum. Nanosuspension formulation was prepared by using sodium lauryl sulphate, hydroxy propyl
methyl cellulose, poly vinyl alcohol and polysorbate 80. The formulated nanosuspension was further accessed to identify
particle size, Polydispersity index, and zeta potential value. Characterization and stability studies of optimize.. View more»