PMC/PubMed Indexed Articles
Indexed In
- Open J Gate
- Academic Keys
- JournalTOCs
- ResearchBible
- RefSeek
- Hamdard University
- EBSCO A-Z
- OCLC- WorldCat
- Publons
- Geneva Foundation for Medical Education and Research
- Euro Pub
- Google Scholar
Useful Links
Share This Page
Journal Flyer
Open Access Journals
- Agri and Aquaculture
- Biochemistry
- Bioinformatics & Systems Biology
- Business & Management
- Chemistry
- Clinical Sciences
- Engineering
- Food & Nutrition
- General Science
- Genetics & Molecular Biology
- Immunology & Microbiology
- Medical Sciences
- Neuroscience & Psychology
- Nursing & Health Care
- Pharmaceutical Sciences
Stephen C Allen
DrStephen Allen,, Department of Medicine, The Royal Bournemouth Hospital, Castle Lane East, Bournemouth, BH7 7DW, UK
Publications
-
Review Article
Inflammation, Delirium, Dementia and Ageing Brain Phenotypes: A Short Review and the Need for New Approaches to Explore Immune System Complexity
Author(s): Stephen C Allen*
Ageing is associated with persisting systemic inflammation, both in chronic form and as delayed resolution after acute inflammatory illnesses. The clearest markers of this are raised blood concentrations of pro-inflammatory cytokines and other chemokines that are involved in mediating an inflammatory state, and C-reactive protein as general indicator of inflammation. This condition of “inflammaging” is linked causally in a complex and reciprocal manner with several diseases that are prevalent in older people including a tendency to develop delirium during acute perturbations of brain function, and to a predisposition to dementia and other age-associated neurodegenerative conditions. There is evidence of a key role of cytokines both in the aetiologies of such diseases and in the immune modulation processes that reduce inflammation, and evidence that in.. View more»