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Stefan Pintar
Department of Electrical Engineering and Information Technology, Technical University Dortmund, Germany
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Commentary
Peptide Nanomaterials Self-Assembled at Biointerfaces: Molecular Engineering and Biomedical Applications
Author(s): Stefan Pintar*
Peptide nanomaterials, formed through self-assembly at biointerfaces, present a promising avenue in biomedical research due to their tunable properties and versatile applications. This review discusses the fundamental principles underlying the selfassembly of peptide nanomaterials, emphasizing molecular engineering strategies that govern their structure and function. Key non-covalent interactions such as hydrogen bonding, hydrophobic interactions, electrostatic forces, and π-π stacking drive the spontaneous organization of peptides into various nanostructures including nanofibers, nanotubes, and hydrogels. The molecular design of peptide sequences, coupled with considerations of amphiphilicity, charge distribution, and length, allows precise control over nanostructure formation and properties. In biomedical applications, peptide nanomaterials demonstrate significant potential in.. View more»