Department of Haematology, Centre Henri Becquerel, Rouen, France
Dr. Stéphane Lepretre has the affiliation of Department of Haematology, Centre Henri Becquerel, Rouen, France. His study interests major on Hematological Malignancies, Leukemia, Myelodysplastic Syndromes.
Case Report
Fatal Invasive Trichosporonosis Caused by Trichosporon inkin after Allogeneic Stem Cell Transplant for very Severe Idiopathic Aplastic Anemia
Author(s): Daphné Krzisch, Vincent Camus, Marion David, Gilles Gargala and Stéphane Lepretre*
Invasive Trichosporon inkin fungal infections are rare and unusual, occurring nearly exclusively in immunocompromised patients experiencing prolonged neutropenia during treatment of malignant hemopathies or other immunodeficiency conditions. We report a case of a 27-year-old patient with severe aplastic anemia who developed Trichosporon inkin sepsis with skin lesions during aplasia after myeloablative allogeneic stem cell transplant. He was treated with liposomal amphotericin B but died from multiple organ failure. We then discuss the epidemiological, clinical and therapeutic features of these serious fungal infections compared to the published data. .. View more»