Department of Biotechnology, Kempegowda Institute of Medical Sciences, Bengaluru, India
Research Article
Whole Genome Sequencing of Omicron Identified Multiple Outbreaks and Introduction Events in India during November 2021 and January 2022
Author(s): Shreedhanya D. Marathe, Varun Shamanna, Geetha Nagaraj, Nischita S, Muthumeenakshi Bhaskaran and K.L Ravi Kumar*
The Variant of Concern (VOC), Omicron is the predominant variant circulating throughout the world of the SARS CoV-2 pandemic during the third wave including India. The world health organisation has designated this highly mutated variant as a VOC due to its high transmissibility and risk of reinfection. Whole genome sequencing and analysis were performed for SARS-CoV-2 PCR positive samples between December 2021 to January 2022. From the 133 Omicron variants detected, genomic analysis was carried out by contextualizing them with 1586 complete genomes of Omicron from India obtained from GISAID. The Omicron variant prevalence in India has increased in a log phase within 3 months in most of the metropolitan cities. With the limited sequencing data available, it was identified that the sublineage BA.1 was predominant in India from November 2021 to January 2022. Further, the first sequence o.. View more»