Shin Takasawa

Department of Biochemistry, Nara Medical University, Kashihara, Japan

Publications
  • Mini Review   
    Molecular Biological Researches in Sleep Apnea Syndrome (SAS)/Intermittent Hypoxia
    Author(s): Shin Takasawa*

    Sleep Apnea Syndrome (SAS) exposes cells throughout the body to Intermittent Hypoxia (IH). IH resulted from SAS is a main risk factor not only for hypertension, cardiac disorders, decreased insulin secretion, and insulin resistance but also for vascular dysfunction. We have reported correlations between IH and decreased glucose-induced insulin secretion from pancreatic β-cells, insulin resistance in skeletal muscle cells and adipocytes, hypertension via upregulation of renin, dopamine β-hydroxylase, and phenylethanolamine N-methyltransferase, and cardiac disorders. In this mini-review, I would like to discuss the problems of IH research in SAS using most recent vascular endothelial cell dysfunction as an example... View more»

    DOI: 10.35248/2155-9627.24.15.480

    Abstract HTML PDF