Department of Public Health, La Trobe University, Bundoora, Victoria, Australia
Shaun Francis Purkiss is currently working at the Department of Public Health, La Trobe University, Bundoora, Victoria, Australia and his specialization is in Public Health, Pharmaceutical Science, Diabetes.
Research Article
Duration of Antidepressant Use and Risk of New Onset Drug Treated Diabetes Derived from Australian Administrative Data
Author(s): Shaun Francis Purkiss*
Introduction: Treatment with antidepressants may be associated with a risk of diabetes. Direct drug effects might play a role, but weight gain and impaired glucose regulation are other factors that may contribute to diabetes risk.
Objective: We have utilised an Australian administrative pharmaceutical database to examine the association of new onset drug-treated diabetes with specific antidepressant treatments and durations.
Methods: A longitudinal cohort study with quasi-experimental design using administrative pharmaceutical data was performed. Uninterrupted treatments of 0.5-4 years with specific antidepressant agents prescribed to individuals were defined and the relative risks of new-onset drug treated diabetes calculated for age, sex, and treatment duration.
Results: Seven antidepre.. View more»