National Institute of Tuberculosis and Respiratory Diseases, India
Dr. Amit Sharma has completed his MBBS and MD in Pulmonary Medicine from Delhi University at age of 28. He is currently working as a Senior TB and Chest Specialist in NITRD for more than 9 years. He has guided the dissertations of Post Graduate Students and is closely associated with teaching and training activities in NITRD. Post PG experience is of more than 14 Years and has Case Reports published in International Journals as first and second author.
Editorial
Positive Pulmonary Tuberculosis Patients with Acute Respiratory Failure.
Author(s): Sharma A*
Pulmonary tuberculosis (PTB) coupled with Acute Respiratory Failure (ARF) usually heralds a dismal patient outcome1. Admission to the Intensive Care Unit (ICU) along with Invasive mechanical ventilation (IMV) in PTB patients is usually associated with very high mortality2. Non-invasive Ventilation (NIV) when applied early in such patients has the potential to prevent intubation and improve prognosis in terms of reduced morbidity and/or mortality 3. We conducted a prospective study in our Institute where NIV was applied to 35 patients with smearpositive PTB who had concurrent ARF. Fourteen patients (40%) improved on NIV and were later discharged on treatment (survivors). The remaining patients (60%) were candidates for IMV but none survived. Statistically significant predictors of mortality in our study were multiple courses of anti-tubercular treatment in the past, advanced disease a.. View more»