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SH Parvez
CNRS Neuroendocrine Unit, Paris, France
Publications
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Research Article
The Multisystemic origins of Alzheimer’s disease
Author(s): Ewing GW* and SH Parvez
The author discusses the fundamental relationship which exists between sense perception, brain function, and changes of molecular biology and uses Grakov’s mathematical model of the relationship between sense perception, brain function, the autonomic nervous system and physiological systems, and cellular and molecular biology to explain this complex relationship in the Alzheimer patient. This paper illustrates that changes of molecular biology (the a-Beta amyloid protein and fibrils) are the consequence of the failure of the brain to optimise the function of the physiological systems, in particular sleep, posture, intercellular pH and blood glucose. It is shown that Alzheimer’s Disease is a polygenomic, multisystemic and multi-pathological indication, with cognitive and neurological origins, and that knowledge of this mechanism has the pot.. View more»