Department of Biochemistry, Ondokuz Mayis University, Samsun, Turkey
Dr. Sena Cenesiz Licence ANKARA UNIVERSITY /completed degree in 1996 from ANKARA UNIVERSITY and in 1996 completed Doctorate from KAFKAS UNIVERSITY- In 2003 working as a Assist. associate professorship in ONDOKUZ MAYIS UNIVERSITY After that in 2005 working as associate professorship ONDOKUZ MAYIS UNIVERSITY
Research Article
The Effects of Quercetin on the Fluorosis Toxicity in Kidney of Mice
Author(s): Ercan Karabulut*, Onder Otlu, Ahu Pakdemirli, Murat Yar�±m, Ayris Salt and Sena Cenesiz
There are many uses of fluorine compounds which we are exposed to in daily life unaware, have toxic effects on tissues. Demonstrating anti-oxidative effect is one of the most important biological properties of phenolic substances. It has been identified in vitro studies of antioxidant flavonoids such as quercetin that it reduces the oxidation of lowdensity lipoproteins and protects cells from toxicity. In this study we aimed to determine the effect of quercetin on the fluorosis toxicity in kidney. In the study, 40 Swiss albino male mice were used. The kidney tissues and blood samples were taken from the mice in each group. Total Oxidant Status and Total Antioxidant Status were measured by the commercially available kits. Ceruloplasmin and MDA levels are measured by chlorometric methods. Kidney tissues stained with Hematoxylin-Eosin dye and investigated under the light microscope. Hist.. View more»