Department of Pharmaceutical Chemistry, KYDSCT’s College of Pharmacy, Sakegaon Bhusawal, Maharashtra, India
Sandip S Chaudhari is the Department of Pharmaceutical Chemistry, KYDSCTâs College of Pharmacy, Sakegaon Bhusawal city, Maharashtra state, India. His specialization is Pharmaceutical Chemistry. His interested in Chemistry.
Research Article
Quantitative Estimation of Dapagliflozin in Blood Plasma by Using UV
Spectroscopy
Author(s): Bhagwat J Bodade, Dhiraj A Kanade and Sandip S Chaudhari*
An accurate, precise and reproducible quantitative estimation of dapagliflozin in blood plasma method were developed. Spectrophotometric estimation was done by absorption method followed by using sample of blood plasma of patient who are given dapagliflozin tablet. In this method λmax for DAPA was selected at 224 nm at concentration range of 20-100 μg/ml for DAPA in UV spectrophotometric method (the value of r2=0.994). The developed methods were validated according to ICH guidelines and values of accuracy, precision and other statistical analysis were found to be in good accordance with the prescribed values. Therefore this method is useful for quantitative estimation of drug and amount of drug absorb in blood plasma. .. View more»