Department of Chemistry and Environmental Sciences, University of Maragheh, Iran
Research Article
Use the Best of MNPS-IHSP Nanoparticles with Coating of Ampicillin Antibiotic, as Bactericidal Properties
Author(s): Mansour Binandeh*, Farokh Karimi and Sadegh Rostamnia
In this research, we have tried to maximize the potential of Fe3O4 magnetic nanoparticles coated by SiO2 and
immobilized with imidazoline hetropolymer (MNPS-IHSP) to stabilize and release the drug molecule called ampicillin
(amp). In this purpose, nanoparticles of 50 nm in size were investigated under a tool such as; FT-IR, SEM, EDX
detection and its structure in-vitro conditions. MNPS-IHSP nanoparticles is a specific and suitable nanocomposite
that it have a mission as well as stabilizing the amp in the presence of silica coating (electrostatic bonding), that it
called MNPS-IHSPA, and the results indicate a stabilization with a higher percentage of 85. It was beneficial to
the silica coating. This measurement was performed by a UV-V is spectrophotometer analysis. Ultimately, in-vitro
conditions, these magnetic nanoparticles that w.. View more»