Department of Biological Sciences, University of Texas, El Paso, Texas, USA; 4Orion Research & Management Services Inc., 205 FM 107, Gatesville, Texas 76528, USA
Mark Rowland’s research concerned the conditional expression of alternative minor and major male phenotypes in scarab beetles. His projects dealt with: (1) Macroevolutionary behavior of horn expression thresholds as a function of defined phylogenetic scale in the dynastine genus Xylotrupes(Rowland 2003); (2) Development of a coherent quantitative system that effectively models demographic and evolutionary.
Research
Evaluation of the Immunogenicity of a Mutagenized Rift Valley Fever MP-12 and a Recombinant Rift Valley Fever arMP12ΔNsm21/384 Vaccine Candidates in Indigenous Species of Cattle, Sheep, and Goats in Tanzania
Author(s): Salekwa LP, Nyundo SB, Adamson EK, Matiko MK, Bettinger GE, Rowland JM, Palermo PM, Wambura PN, Morrill JC and Watts DM*
Objective: Rift valley fever virus (RVFV) is the cause of devastating outbreaks among domestic ruminants and humans in most African countries and in the Arabian Peninsula. Current efforts to develop and evaluate an improved veterinary vaccine to prevent RVF disease among domestic ruminants includes a live attenuated RVFV MP-12 candidate and a recombinant vaccine referred to as arMP12ΔNsm21/384 that was derived from the RVF MP-12 vaccine candidate. The aim of this study was to evaluate these RVFV vaccine candidates in domestic ruminants in Tanzania.
Methods: Six to nine months old goats (Capra aegagrus hircus), calves (Bos taurus indicus) and sheep (Ovis aries) were vaccinated subcutaneously with one ml each of 1 × 105 plaque forming units (PFU)/ml of the RVF MP-12 and/or the arMP-12ΔNSm21/384 candidate vaccines. .. View more»