Department of Immunology, University of Toronto, Toronto Geberal Hospital, Ontario, Canada
Reginald M Gorczynski is currently working as a Professor in the Department of Immunology at the University of Toronto. His research interests include Immunology, Immunomodulation. Reginald M Gorczynski is serving as an editorial member and reviewer of several international reputed journals. Reginald M Gorczynski has successfully completed his Administrative responsibilities. Reginald M Gorczynski has authored many research articles/books related to Medicine, Immunology, Vaccines.
Review Article
Personalizing Vaccination for Infectious Disease in the 21st Century
Author(s): Reginald M Gorczynski*
Current approaches to vaccination have several underlying assumptions, namely that following immunization most
individuals are at similar risk of the disease considered; will react immunologically in the same way (with protective
antibodies and/or cell-mediated reactivity) with equivalent and minimal side effects; and that vaccination dosing
and frequency of administration does not vary in the population at large. As a result, a widespread delivery of
vaccines has been achieved for a number of infectious diseases, with effective control for many of those. It is clear
that a weakness of this approach, made manifest with our increasing knowledge of the genomic and proteomic
approach to medicine which has come to the fore in the last decade or so, is that it discounts the growing evidence
for individual variability in risk; in immune responsiveness; and in response t.. View more»