Journal of Bacteriology & Parasitology

Department of Medical Laboratory Sciences, Hunter College, Manhattan, New York, USA

Biography

Regina Linder is Professor Emerita, Medical Laboratory Sciences (MLS), Hunter College (CUNY). A medical microbiologist, her research focuses on the collaborative cytotoxins of pathogenic and commensal bacteria, insects and marine organisms. At Hunter since 1982, Regina taught clinical microbiology and served as program director of MLS from 1989 to 2007. 

Publications

• Research Article   
  Cooperative Cytotoxins: A New Look at an Old Observation of Bacterial Crosstalk
  Author(s): Regina Linder* and Camille D. McIntyre
  
  Cooperative (or synergistic) hemolysis, the ability of two bacterial species to jointly lyse erythrocytes, has long been recognized as a helpful tool in the identification of common pathogens (i.e. the CAMP reaction between Streptococcus agalactiae and Staphylococcus aureus). However, to examine these biological partnerships separately from their use in the diagnostic lab provides new perspectives on toxicity to host tissue during infections and in health. Many examples of such pairings exist, and typically reflect the sequential action of a phospholipase (e.g., PLC from Staphylococcus aureus or Clostridium perfringens), followed by a second bacterial toxin acting on the altered membrane, e.g. the CAMP protein of group B streptococci, or the cholesterol oxidase of Rhodococcus equi. Commonly occurring cooperative cytotoxic part.. View more»
  

  DOI: 10.35248/2155-9597.19.10.362

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