Institute of Biotechnology, Vietnam Academy of Science and Technology, 18 Hoang Quoc Viet, Cau Giay, Hanoi, Vietnam
Quang Huan Le is affiliated to Institute of Biotechnology. He is a recipient of many awards and grants for his valuable contributions and discoveries in major area of subject research. His international experience includes various programs, contributions and participation in different countries for diverse fields of study. His research interests reflect in his wide range of publications in various national and international journals.
Image Article
Study on screening Vietnamese herbs with antiviral activity to create products to support treatment of some diseases caused by RNA-virus
Author(s): Quang Huan Le*, The Quan Nguyen, Hoang Minh Duc, Thi Tam Quyen Doan, Thi Huyen Trang Chu, Thu Thao Dao and Thi Thanh Huong Ha
Using information technology and traditional oriental medicine research, we have screened 5 Vietnamese herbs that contain active ingredients with antiviral effects. Andrographispaniculata, Syzygiumaromaum, Zingiber officinale Rose, Houttuyniacordata, Glycyrrhizauralensis Fisch. The active ingredients in herbs are extracted by ultrasound in a water-ethanol solvent system and made in the form of a nanometer complex, then mixed in specified proportions to form the product. The product was evaluated cytotoxicity by MTT (3-(4,5-dimethylthiazolyl-2)-2, 5-diphenyltetrazolium bromide) assay and evaluated the growth inhibition effect of H5N1 virus. Result: The complex of active ingredients in the composition has the nanometer size, the main size is 443 nm, the zeta potential is -11.9 mV. The inhibitory activity of the H5N1 virus was dose-dependent, and a concentration of 3 mg/mL completely inh.. View more»