PMC/PubMed Indexed Articles
Indexed In
- Open J Gate
- Genamics JournalSeek
- Academic Keys
- JournalTOCs
- ResearchBible
- China National Knowledge Infrastructure (CNKI)
- Scimago
- Ulrich's Periodicals Directory
- Electronic Journals Library
- RefSeek
- Hamdard University
- EBSCO A-Z
- OCLC- WorldCat
- SWB online catalog
- Virtual Library of Biology (vifabio)
- Publons
- MIAR
- Scientific Indexing Services (SIS)
- Euro Pub
- Google Scholar
Useful Links
Share This Page
Journal Flyer
Open Access Journals
- Agri and Aquaculture
- Biochemistry
- Bioinformatics & Systems Biology
- Business & Management
- Chemistry
- Clinical Sciences
- Engineering
- Food & Nutrition
- General Science
- Genetics & Molecular Biology
- Immunology & Microbiology
- Medical Sciences
- Neuroscience & Psychology
- Nursing & Health Care
- Pharmaceutical Sciences
Pranav Shende
Department of Nanomedicine, Houston Methodist Research Institute, USA
Publications
-
Mini Review
Determine Tumor Site-Dependent Transport Properties Delivery of Nanotherapeutics and Their Efficacy
Author(s): Pranav Shende*
Therapeutic effectiveness of anticancer medicines delivered systemically may be hampered by insufficient distribution of the medications to tumours. Can create therapeutic resistance based on drug delivery. PEGylated liposomal doxorubicin (PLD), for example, uses an increased permeability and retention effect to preferentially accumulate in tumours. Their clinical results and anticancer effects, however, vary widely amongst tumour types and are minimal. We looked into whether the tumour site affected the quantity and effectiveness of PLD delivered to tumours. We created mouse breast models with orthotopic primary tumours or liver metastases. Utilising 4 T1 cells for cancer PLD effectively treated cancers that developed in primary mammary tissue. but not in the liver, locations. We discovered that variations in treatment effectiveness were not caused by the intrinsic biological defence.. View more»