Journal of Bioequivalence & Bioavailability

International Bio Service Co., Ltd., 888 Golden Jubilee Medical Center, Mahidol University, Nakhon Pathom 73170, Thailand

Biography

Dr. Porranee Puranajoti currently works in the International Bio Service Co., Ltd., 888 Golden Jubilee Medical Center, Mahidol University, Nakhon Pathom 73170, Thailand. His research interest includes Bioequivalence; Pharmacokinetics; LC-MS/MS

Publications

• Research   
  Bioequivalence Study of Favipiravir 200 mg Tablets in Healthy Thai Volunteers under Fasting Conditions
  Author(s): Ekawan Yoosakul, Anas Sunhem, Vipada Khaowroongrueng*, Lalinthip Saeaue, Busarat Karachot, Isariya Techatanawat, Porranee Puranajoti and Praphassorn Surawattanawan
  
  Favipiravir is a broad spectrum antiviral against RNA viruses. It has been considered as a promising treatment strategy for a pandemic of Coronavirus Disease 2019 (COVID-19). During this urgent need, the Government Pharmaceutical Organization (GPO), Thailand had developed favipiravir 200 mg tablet formulation (FAVIR®). A randomized, two-treatment, two-period, two-sequence, single-dose, crossover study was designed to determine the bioequivalence of two favipiravir 200 mg tablet formulations, FAVIR® and AVIGAN® under fasting conditions. The plasma-concentration time profiles were used to characterize the rate and extent of absorption of favipiravir in the test and reference products. The pharmacokinetics parameters were calculated using non-compartmental model. The analysis of variance did not show any significant differ.. View more»
  

  DOI: 10.35248/0975-0851.21.13.436

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