Asian Healthcare Foundation, AIG Hospitals, Gachibowli, Hyderabad, India
Research Article
Methylene Blue in Treatment of Severe COVID-19 Patients: A Large Cohort Study
Author(s): Bhanu Prakash Reddy Attunuru*, Madhusudhan Reddy Lingala, Podduturi Naveen Chander Reddy, Anand V Kulkarni, Sasikala Mitnala and Duvvur Nageshwar Reddy
Background and objectives: As there are limited treatment options in treatment severe COVID-19 disease we aim to evaluate the role of methylene blue in management of severe COVID-19 disease. The primary objective was to assess the survival benefit of methylene blue in severe COVID-19 disease. The secondary objective was to compare the duration of hospital stay, the requirement of invasive mechanical ventilation, the development of thrombotic complications and the change in inflammatory markers at discharge/death among the two groups. (SMT group and MB group).
Materials and methods: This is a single-center retrospective observational study of 362 patients admitted with severe COVID-19 disease from July 2020 to February 2021 in a tertiary care hospital during first wave of COVID-19 in India. 254 patients received MB at a dose of 1 mg/kg body w.. View more»